The role of gene architecture in gene expression

Authors

  • Karla Neugebauer Max Planck Institute of Molecular Cell Biology and Genetics, Dresden

DOI:

https://doi.org/10.14806/ej.19.A.678

Keywords:

gene expression, transcription, splicing, gene architecture

Abstract

Recent global studies in several species have indicated that most intron removal is co-transcriptional, underscoring the potential for coupling between the transcription and splicing machineries as well as chromatin.Our work is conducted in mammalian tissue culture cells, zebrafish embryos, and budding and fission yeasts. This work will report on a new study investigating the role of gene architecture in the activation of transcriptional programs in zebrafish embryos.

Author Biography

  • Karla Neugebauer, Max Planck Institute of Molecular Cell Biology and Genetics, Dresden
    Senior gropu Leader 

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Published

2013-04-17

Issue

Vol. 19: Supplement A

Section

Keynote Lectures

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