Pipeliner: A tool to evaluate NGS pipelines and optimize experimental designs for resequencing studies.

Authors

  • Bruno Nevado Centre for Research in Agricultural Genomics (CRAG), Barcelona
  • Miguel Perez-Enciso 1 Centre for Research in Agricultural Genomics (CRAG), Barcelona 2 Universitat Autononoma de Barcelona, Bellaterra 3 Institut Catala de Recerca i Estudis Avancats (ICREA), Barcelona

DOI:

https://doi.org/10.14806/ej.19.A.649

Abstract

The choice of technology and bioinformatics' approach is central in the analysis of Next-Generation-Sequencing experiments. The pace with which new software and methodological guidelines are published, together with the fact that many of these choices will depend on the particularities of the study-system, mean researchers are often unable to produce informed decisions regarding these central questions. To address these issues, we introduce Pipeliner, a tool to simulate and validate the performance of NGS analysis pipelines, and optimize experimental designs.

Author Biography

  • Bruno Nevado, Centre for Research in Agricultural Genomics (CRAG), Barcelona

    Numerical Genomics group

    Postdoctoral researcher

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Published

2013-04-08

Issue

Vol. 19: Supplement A

Section

Posters

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