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As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines.

  • All submissions must meet the following requirements.

    • The manuscript has not been previously published, nor is it under evaluation by another journal.
    • The submited file is an OpenOffice and Microsoft Word format.
    • The text is single-spaced, uses a 12-point font; all illustrations, figures, and tables are placed at the end.
    • The text adheres to the stylistic and bibliographic requirements outlined in the Author Guidelines, which is found in About the Journal.
    • If submitting to a peer-reviewed section of the journal, the instructions in Ensuring a Blind Review have been followed.

Publication ethics and publication malpractice statement

Archive of Clinical Cases encourages authors to strive for, and adhere themselves to, the International standards for authors of scholarly research publications developed by The Committee on Publication Ethics (COPE).  

Archive of Clinical Cases follows the ICMJE's Recommendations for the Conduct, Reporting, Editing and Publication of Scholarly Work in Medical Journals.

Reporting Guidelines for Case Reports according to EQUATOR Network (See CARE Checklist 2013)

Archive of Clinical Cases uses PlagScan and Copyleaks to identify paraphrased and similar content in order to detect and prevent plagiarism.

The image shows our cooperation with the online plagiarism detection service PlagScan

Title Page - indicate a concise and meaningful title for the article.

In order to assure a double blind reviewing process, the manuscript should not contain the authors' names, institutional addresses, phone numbers and email addresses.

Authors' contribution

An 'author' is generally considered to be a person who’s intellectual contribution was substantive to a published article. According to the ICMJE guidelines, the following criteria account to qualify a person as author: i) substantial contributions to conceptualization, supervision and design, data curation, or formal analysis and interpretation and validation of data; ii) been involved in writing the original draft of the manuscript, editing or revising it; iii) approving the final version to be published. The contribution of each author should be significant for the main portions of the content; and iv) agreed to be responsible for all parts of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. For more information, visit: http://www.icmje.org/recommendations/browse/roles-and-responsibilities/defining-the-role-of-authors-and-contributors.html

We recommend to limit the number of authors to maximum 7 for Case report.

Abstract should be provided on the 2nd page of the manuscript. It must include no more than 250 words. The abstract should not contain any undefined abbreviations or references.

We recommend the use of 5-7 keywords, significant for the topic of the manuscript.

Text Formatting All manuscripts should be submitted in Word (*.doc – older Word versions or *.docx format – Word 2007 or higher). • The text will be typed using a plain font (e.g., 12-point Times Roman). • If necessary, use italics for emphasis. • Page numbers will be inserted automatically by the page numbering function. • Field functions will be avoided. • No tab stops or other commands for indents should be used. • To design tables, use the table function, and do not import spreadsheets. • For equations, Equation Editor or MathType in word are recommended. • Save your file in docx format (Word 2007 or higher) or doc format (older Word versions)

Abbreviations Abbreviations should be defined at first use in the main text of the manuscript and then consistently used. A list of abbreviations can be added at the end of the manuscript, before the competing interests and authors' contributions.

Footnotes No footnotes or endnotes are allowed.

Acknowledgments Acknowledgments of people, grants, funds, etc. should be placed at the end of the manuscript right before References.

Scientific style It is mandatory to use internationally accepted signs and symbols for units (SI units).

Reference list References from the literature cited in the manuscript should be indicated in the reference list (at the end of the manuscript) ordered as they appear in the text. Reference list may include only the works that have been published or accepted for publication. If the authors want to mention personal communications and unpublished works, these can be done only in the text. We do not encourage self-citations, unless they are significant works. We recommend citing other published case reports that are significant to the presented case. All entries in the list should be numbered consecutively.

Journal article

- with 1-6 authors (include all authors): Koonin EV, Altschul SF, Bork P. BRCA1 protein products: functional motifs. Nat Genet. 1996; 13:266-267.

- with more than 6 authors (include only the first 3 authors, et al.): Franssen CFM, Gans ROB, Arends B, et al. Differences between anti-myeloperoxidase- and anti-proteinase 3-associated renal disease. Kidney Int. 1995; 47:193–199.

Article within a journal supplement Orengo CA, Bray JE, Hubbard T, LoConte L, Sillitoe I: Analysis and assessment of ab initio three-dimensional prediction, secondary structure, and contacts prediction. Proteins. 1999; 43(Suppl 3):149-170.

Published abstract Zvaifler NJ, Burger JA, Marinova-Mutafchieva L, Taylor P, Maini RN. Mesenchymal cells, stromal derived factor-1 and rheumatoid arthritis [abstract]. Arthritis Rheum. 1999; 42:s250.

Article in a conference proceedings Jones X. Zeolites and synthetic mechanisms. In Proceedings of the First National Conference on Porous Sieves: 27-30 June 1996; Baltimore. Edited by Smith Y. Stoneham: Butterworth-Heinemann; 1996:16-27.

Book Kansky J, Bowling B. Clinical Ophtalmology - A Systematic Approach, 7th Edition. Philadelphia: Elsevier Saunders, 2011.

Book chapter, or article within a book Schnepf E. From prey via endosymbiont to plastids: comparative studies in dinoflagellates. In Lewin RA (Ed.) Origins of Plastids. Volume 2. 2nd edition. New York: Chapman and Hall; 1993:53-76.

Book with institutional author Advisory Committee on Genetic Modification: Annual Report. London; 1999.

PhD thesis Kohavi R: Wrappers for performance enhancement and oblivious decision graphs. PhD thesis. Stanford University, Computer Science Department; 1995.

Link / URL National Institute of Neurological Disorders and Stroke-NINDS Neurofibromatosis Information Page [http://www.ninds.nih.gov/disorders/neurofibromatosis/neurofibromatosis.htm available at mm.dd.yyyy]

Link / URL with author(s) Corpas M: The Crowdfunding Genome Project: a personal genomics community with open source values [http://blogs.biomedcentral.com/bmcblog/2012/07/16/the-crowdfunding-genome-project-a-personal-genomics-community-with-open-source-values/ available at mm.dd.yyyy]

Clinical trial registration record with persistent identifier Mendelow, AD (2006): Surgical Trial in Lobar Intracerebral Haemorrhage. Current Controlled Trials. http://dx.doi.org/10.1186/ISRCTN22153967 Always use the standard abbreviation of a journal’s name according to the ISSN List of Title Word Abbreviations, as in www.issn.org/2-22661-LTWA-online.php

Tables All tables are to be numbered using Arabic numerals. • Similar to Figures, Tables should always be cited in text, and numbered consecutively. • Each table must be provided with a caption (title) explaining the table.

Artwork and Illustrations Guidelines Electronic format submission for artwork and photographs, line drawings, is a must.

Electronic Figure Submission • Figures should have a minimum resolution of 600 dpi. • For vector graphics, the preferred format is EPS; for halftones, please use TIFF format.. • Name your figure files with "Fig" and the figure number, e.g., Fig1.eps. • Each figure must be provided with a caption (title) explaining the figure. • Figure should always be cited in text in consecutive numerical order in parentheses (Figure 1).

Line Art. Figures • Black and white graphic with no shading. • Faint lines and/or lettering are not encouraged and all lines and lettering within the figures should be legible at final size. • Scanned line drawings should have a minimum resolution of 200 dpi. • Color figures should be submitted as RGB (8 bits per channel). Figure Lettering • To add lettering, it is best to use Helvetica or Arial (sans serif fonts). Lettering should be editable. • Keep lettering consistently sized throughout the whole manuscript. • No variance of type size within an illustration are permitted, unless necessary. • We recommend avoiding effects such as shading, outline letters, etc. • Do not include titles or captions within the figures/illustrations.

Figure Numbering • All figures are to be numbered using Arabic numerals. • Figures should always be cited in text in consecutive numerical order. • Figure parts should be denoted by lowercase letters (a, b, c, etc.).

Figure Captions • Each figure should have a caption which must be concise and describe what the figure depicts. The caption position is at the end of the manuscript. • Figure captions begin with the term Fig., followed by the figure number. In text, the figure must be mentioned with “Figure” and the number of the figure.

Permissions • Figures that have already been published in other published papers/books/websites may be included in the manuscript after obtaining permission from the copyright owner(s). Some publishers do not grant electronic rights for free. UMF Gr. T Popa Publishing house is not able to refund the costs for obtaining these permissions.



Authors are required to complete a declaration of competing interests. In case of competing interests, these should be listed at the end of published articles. In case there are no competing interests, the sentence can be 'The author(s) declare that they have no competing interests'.
Conflicts of interest represent - according to PLOS - any interference with the objectiveness of the information provided in the article, or possibility to be reasonably perceived as such, potentially biasing the editorial decision-making process. Conflict of interests may arise when secondary interests (such as financial benefits or personal issues) could have repercussions on professional judgment of primary interest (for example patient’s consent). As it is difficult for individual readers to objectively evaluate whether a competing interest could have influenced the presentation, the reviewing, or the editors’ decision regarding publishing a given manuscript, we require the authors to fill in and submit the ICMJE Form for Disclosure of Potential Conflicts of Interest. Since competing interests arise almost inevitably, stating them allows readers to assess more precisely such bias, ensuring transparency regarding any affiliation, relevant financial interest, funding, and donation of medical equipment or other related aspects. A manuscript will not be rejected from publishing simply due to the existence of a competing interest, but failure in disclosing an up-to-date information related to the conflicts of interest may delay the evaluation process of the manuscript. The policy regarding disclosure of such information is unconcealed and applied for all submitted manuscripts: the filled-in information referring to the conflicts of interest will be published in Conflict of interests section of the article. If there is any concern or uncertainty about the relevance of a financial relationship or interest, the correspondent author should contact the editorial office.
Editors and journal staff as authors
Editors and Editorial Board members of Archive of Clinical Cases may submit a manuscript to ACC for evaluation and publication, but this might represent a potential conflict of interest. In these cases, ACC follows the guidelines for good editorial practice recommended by international editorial organizations (e.g., WAME and COPE). The review process of these manuscripts will not imply the submitting editor(s) and will be supervised by a senior editor who will independently evaluate the manuscript and decide. If necessary, in order to minimize the possible bias in reviewing, the reviewing process will be addressed to an outside expert.
At the end of these articles, a short statement (Conflict of interest, Disclaimer) will be communicated listing the editors or the board members as authors


A statement regarding the existence of patient informed consent is mandatory; otherwise the manuscripts will not be peer-reviewed. This is to confirm that the patient granted his informed consent for the present research or case report to be published. A copy of this consent should be available to the editorial office, upon request. Although it is not mandatory to be exactly quoted, we recommend the following phrases to be used: "Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal." Failing to present an appropriate patient informed consent will lead to the rejection of the manuscript.




Archive of Clinical Cases is an Open Access journal and publishing an article in this journal requires an Article Processing Charge (APC). APC will be billed to the corresponding author only after acceptance of the manuscript for publication in its final revised variant. Except from this Article Processing Charge there are no other fees.

The payment instructions will be provided via email to the corresponding author after issuing the invoice.

For manuscripts submitted after 31st of December 2022, the Article Processing Charge is 400 Euro or the equivalent in USD or Romanian Lei.

The names and addresses entered in this journal site will be used exclusively for the stated purposes of this journal and will comply with national legislation on data protection and with the European Union’s General Data Protection Regulation (the ‘GDPR’) that went into effect on May 25, 2018.

Our Site is not intended for children. We do not knowingly collect or maintain the personal information of children under the age of 18. If you are under the age of 18, please do not access our Site at any time or in any manner. We will take appropriate steps to delete the personal information of persons under the age of 18.

Information We May Collect about You

We will collect any information that you provide to us when you:

- submit correspondence to us via our Site;

- register for an account with us or update your profile details;

- submit, edit or review a manuscript depending on whether you are a Submitting Author or Editor or Reviewer;

- subscribe to our mailing list;

- “follow”, “like”, post to or interact with our social media accounts (Facebook or Twitter).

The information you provide to us will include (depending on the circumstances):

- Identity and contact data: title, names, professional addresses, professional email address and professional phone number;
- Account profile data: if you are registering for an account you will also provide a username, password (which can be changed upon your wish), ORCID ID and optional information about your academic and work history, references and any other such similar information as may be required;
- Conflicts of Interest: if you are a Submitting Author, Editor or Reviewer you are obliged to disclose any Conflicts of Interest you may have in relation to the work you are submitting or which you have been assigned to edit or review. Some of the information you disclose may constitute your Sensitive Personal Data.

Information We Receive from Third Parties

In certain circumstances, it is possible that we will receive personal data about you from third parties. For instance:
- ORCID ID: if you are a Submitting Author using the manuscript tracking system to submit a manuscript, you will be required to provide your ORCID ID. By providing your ORCID ID you are authorizing that third-party provider to display certain information about you in accordance with your ORCID account settings;
- Plagiarism checking services: we also use third-party providers to verify information provided by you via your account, including via any articles you submit to us for publication. We use Turnitin and PlagScan software to detect similarities in submitted manuscripts. We also use other third-party databases or websites to confirm your publication history to prevent duplicate submission (including Google, Web of Science/Clarivate Analytics, Scopus, PubMed, and other International Databases).

How We Use Information about You

The information about you will be used for:
- To register you as a user (author/reviewer/editor/reader): when you sign up to use the manuscript processing system, we will use the personal details provided by you;
- To permit your access when using the manuscript tracking system. This way, you will be able to submit a manuscript, to receive notification about the manuscript status or about changes in our Terms of Service or Editorial Policies, asking to review, edit, to upload a revised manuscript, to communicate with the editors.

How We Look after Your Information and How Long We Keep It for

We follow the privacy policy of “privacy by design” by minimizing the amount of personal data we hold about you. Our purpose and actions are targeted to protect your information against any unauthorized access, such as:
- ensuring the physical and digital security of our equipment, electronic system and software by using firewalls, password protection and encryption;
- limiting the access to your personal information to persons of the editorial staff who use it in the course of their work.
We will retain personal information about you for as long as it is necessary in order to provide you with the services that you have requested from us. Upon your request, we can delete your account and erase the information about you, provided when registering.

Help Keep Your Information Safe

You can also contribute in keeping safe your information by:

- composing a strong password or by changing it every 3 months; we also recommend to avoid using the same password for different accounts;
- protecting your login credentials and password and not sharing them with others;
- when using a shared computer, logging out every time you leave the computer is safer;
- informing us in case you suspect a violation of your account.

Your Rights to the Information We Hold about You

Regarding the information that we hold about you, there are some rights, as follows:
- you have the right to be informed about the way in which we use your personal information, protecting your privacy;
- you have the right to ask us not to process your personal data for marketing purposes;
- you have the right to request full access to the personal information that we hold about you; you may also request and receive a copy of any personal information we hold about you;
- you have the right to request us to correct or rectify any inexact information that we hold about you;
- in specific circumstances, you have the right to ask us to stop processing information about you;
- you have the right to withdraw your consent for our use of your information in reliance of your consent; also, you have the right to ask us to limit or to stop processing and/or delete the information that we hold about you.
Still, it is possible that we may need to keep some personal information for our own records.
Should you want to, you may exercise your rights above by contacting the journal via “Contact Us” section.

Changes to This Privacy Policy

It is possible that we make changes to this Privacy Policy. These changes will posted or the Journal’s website and/or notify you by e-mail.
Personal information that we hold about you must be accurate and permanently updated.